In the case of larger business needs however, it’s common to split the application into two separate parts:
One part for the screen forms, queries and program code, typically referred to as a "front-end".
And a separate part just for the data, typically referred to as a "back-end".
The advantages of separating a database into two parts, front-end and back-end:
It's easier to make changes to the front-end while leaving the back-end data alone.
The front-end can be developed with lower cost software and operate on lower cost computers.
While the back-end can be developed with high-performance software and operate from one location on a high-performance computer.
Security is usually better and easier to manage with better back-end databases.
Data integrity is also usually better and easy to manage with better back-end databases.
A Client-Server method is more attainable, where multiple low cost computers can tap into the power and speed
of a single high-performance computer.
Common front-end choices are Microsoft Access and website pages developed with Visual Studio.
Common back-end choices are Microsoft SQL Server, Microsoft SQL Server Express (which is free),
Oracle, MySQL and many others.